Inhibiting the “drug efflux pumps” in bacteria, which function as their defence mechanisms against antibiotics, can mask the effect of mutations that have led to resistance in the form of low-affinity drug binding to target molecules in the cell. This is shown by researchers at Uppsala University in a new study that can provide clues [...]

The drive to discover and develop new oral treatments for tuberculosis (TB), which could save millions of lives in developing countries, will receive an £18 million boost, International Development Minister Ivan Lewis announced.

Scientists in Colorado have discovered a new approach to prevent bacterial infections from taking hold.
Writing in the Journal of Medical Microbiology, Dr Quinn Parks and colleagues describe how they used enzymes against products of the body’s own defence cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both [...]

The British Midlands Development Corporation announced that scientists at The University of Nottingham are leading a major European study to unravel the genetic code of one of the most lethal strains of hospital acquired infections.

Scientists at The University of Nottingham are leading a major European study to unravel the genetic code of one of the most lethal strains of hospital acquired infections.
The 3 million euro, three-year study will use gene knock-out technology developed in Nottingham to study the function of genes in a ’super’ strain of the bacteria Clostridium [...]