Our cells’ molecules form an intricate network of interactions. Today’s techniques, however, can only be used to measure individual molecular reactions outside the cells. Since molecular concentrations are much higher in cells than in the laboratory, scientists suspect that the kinetics of molecular reactions in living cells differ substantially from external probes. „We expected the [...]

The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) using a state-of-the-art protein crystallography beamline at the Advanced Light Source (ALS). These protein motors play pivotal roles in gene expression and replication, and are vital to the survival of all [...]

Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells. The studies used molecular dynamics flexible fitting (MDFF) to examine the interaction of the ribosome with two prominent molecular partners.

Scientists have always wanted to take a closer look at biological systems and materials. From the magnifying glass to the electron microscope, they have developed ever-increasingly sophisticated imaging devices.

Scientists have always wanted to take a closer look at biological systems and materials.
From the magnifying glass to the electron microscope, they have developed ever-increasingly sophisticated imaging devices.