Agios Pharmaceuticals has announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough discovery shows that the mutated form of IDH1 produces a metabolite, 2-hydroxyglutarate (2HG), which may contribute to the formation and malignant progression of [...]

In a breakthrough discovery a research team at The Australian National University has found a critical circuit in the immune system which when faulty causes loss of immunization memory and would explain why some people suffer frequent and repeated infections.

Curemark, LLC, a drug research and development company focused on the treatment of neurological diseases, announced that it has enrolled the first patients in Phase III clinical trials for its autism treatment, CM-AT. The first clinical trial patients have been enrolled at Lake Mary Pediatrics in Orange City, Florida, one of 12 clinical trial sites [...]

A group of nanoengineers, biologists and physicists have used innovative approaches to deduce the internal structure of chromatin, a key player in DNA regulation, to reconcile a longstanding controversy in this field. This new finding could unlock the mystery behind the origin of many diseases such as cancer.