In a newly published clinical trial, patients with metastatic prostate cancer who received a vaccine of harmless poxviruses engineered to spur an immune system attack on prostate tumor cells lived substantially longer than patients who received a placebo vaccine, report researchers at Dana-Farber Cancer Institute and affiliated organizations. The findings will be published by the [...]

The zebrafish, a translucent fish often used as a model of human development and disease, offers unique advantages for studying the cause, growth, and spread of tumors using strategies and methods presented in the current “Cancer Biology” special issue of Zebrafish, a peer-reviewed journal published by Mary Ann Liebert, Inc.

Kai W. Wucherpfennig, MD, PhD, a researcher at Dana-Farber Cancer Institute, has been named a Fellow for the American Association for the Advancement of Science (AAAS). Wucherpfennig was honored for his distinguished contributions in the field of immunology, particularly for advancing the understanding of T-cell receptor recognition and T-cell activation in human autoimmune disease.

Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that it is initiating a Phase 2 clinical study of STA-9090 in patients with advanced gastrointestinal stromal tumors (GIST). This is the sixth clinical study of STA-9090, a potent, synthetic, small [...]

Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) announced the initiation of a Phase 3 registration clinical trial for KRX-0401 (perifosine), the Company’s PI3K/Akt pathway inhibitor, in relapsed / refractory multiple myeloma patients.