A team of scientists from The University of Alabama used worms to reel in information that they hope will lead to a greater understanding of cellular mechanisms that may be exploited to treat epilepsy. In a new research report in the journal GENETICS, the researchers explain how the transparent roundworm, C. elegans, helped them identify [...]

Quark Pharmaceuticals, Inc., a clinical-stage pharmaceutical company committed to discovering, developing and commercializing novel RNA interference (RNAi)-based therapeutics, today announced that James D. Thompson, Ph.D., Vice President, Pharmaceutical Development, will present a case history of QPI-1002, the first systemically administered synthetic siRNA, at the Joint Symposium of the 5th Annual Meeting of Oligonucleotide Therapeutics Society [...]

Most Americans have never heard of magnetic resonance guided focused ultrasound (MRgFUS), yet it is a technology that promises to revolutionize medical care around the world.
“We’re at the same point with focused ultrasound as we were with diagnostic MRIs several decades ago,” says Neal F. Kassell, M.D., a professor of neurosurgery at the University of [...]

Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced that the US Food and Drug Administration (FDA) has reviewed and accepted an Investigational New Drug (IND) application to initiate an open-label, repeat-dosing Phase 1 clinical trial (SB-728-T-902) of the company’s ZFN-based therapeutic, SB-728-T. A single dose Phase 1 clinical study of SB-728-T was initiated in February 2009 and [...]

Mice who inherit a particular chromosomal duplication from their fathers show many behaviors associated with human autism, researchers report in the June 26th issue of the journal Cell, a Cell Press Publication. The duplicated chromosomal region in mice is the equivalent of human chromosome 15q11-13, the most frequent cytogenetic abnormality observed in autism, accounting for [...]